noun
definition
The membrane of cells that forms the wall of a blastocyst during early pregnancy, providing nutrients to the embryo and later developing into part of the placenta.
Examples of trophoblast in a Sentence
One example is the 5T4 oncofoetal antigen originally defined by a monoclonal antibody raised against human trophoblast.
This interface, consisting of the maternal decidua and the invading placental trophoblast, is exposed to profound changes in oxygen tension during pregnancy.
Molar disease expressed P2Y6 in the villous trophoblast but not in the proliferative intermediate trophoblast, recapitulating the pattern of first-trimester placenta.
In this paper we hypothesized that invasive trophoblast released vasodilators which would dilate spiral arteries as an initial step in the physiology of transformation.
Kliman and the team identified trophoblast inclusions by performing microscopic examinations of placental tissues.
We have further utilized in-vitro models to investigate the role of glucocorticoids on trophoblast function (proliferation, differentiation and invasion).
However, the change in NEP expression upon trophoblast differentiation remains to be clarified.
Thus, in vitro MMP9 activity appears not to be essential for trophoblast migration.