definition
Any of a group of naturally occurring lipids derived from the C20 acid prostanoic acid; they have a number of physiological functions and may be considered to be hormones.
It exerts its effects directly in inflamed tissues underlying the site of application, mainly by inhibiting prostaglandin biosynthesis.
Misoprostol is cheaper than Prostaglandin E2, and apparently the induction to delivery interval is reduced, but uterine hyperstimulation appears more likely.
The highest risk was for women who had had prostaglandin gel (4.5% ), tho most of them had also had oxytocin.
The only orally active prostaglandin E1 analog on the market is Cytotec.
Two other effects of aspirin are consequences of action on prostaglandin synthesis.
The anti-inflammatory activity of NSAIDs in the rat paw edema test has been correlated with their ability to inhibit prostaglandin synthetase.
The mechanism of action like that of other NSAIDS may be related to prostaglandin synthetase inhibition.
The formula has since been changed and is now latanoprost and other prostaglandin free.