definition
A small colorless disk-shaped particle found in the blood of mammals, which plays an important role in the formation of blood clots.
It works by preventing the formation of a chemical called cyclic amp in blood platelets.
Now, 40% of adult therapeutic doses (ATD) of platelets collected by the NBS are collected by apheresis.
Platelets from men and women with diabetes are often hypersensitive in vitro to platelet aggregating agents.
The remaining platelets are then transfused back into the patient.
Platelets, apheresis means a concentrated suspension of blood platelets obtained by apheresis.
What more could the NBS do to reduce the risk of bacterial contamination of platelets?
Donors might be especially called to a clinic to provide HLA class I matched platelets for a certain patient.
Images include basophils, monocytes, eosinophils neutrophils, lymphocytes, and platelets.
However, at presentation with relapse, she had received 2 units of red cells and 2 units of platelets which were not irradiated.
Occasionally, if an appropriate product is not available, it may be necessary to use RhD positive platelets.
The recipient (58 year old male) suffered fatal septic shock after transfusion with a 2-day old unit of pooled platelets.
In patients dependent on platelet transfusion, HPA antibodies may be a cause of refractoriness to random donor platelets.
Alternatively selection of compatible platelets by crossmatching can be considered.
Rhesus D negative women of childbearing age should receive Rhesus D negative platelets.
The patient with AML was receiving multiple transfusions of both red cells and platelets, and thus presented as a case of platelet refractoriness.
However, my blood platelets were not rising, nor were my liver enzymes decreasing.
In some patients with HLA antibodies, HPA antibodies may also be present requiring donor platelets matched for both type of antibodies.
Both Rams head and Spiral wedging involve the folding of the clay on itself too build up an ever tightening spiral of clay platelets.
Aspirin is sometimes used in children with heart conditions as it reduces the stickiness of the platelets in the blood.
Thrombin activation of the platelets was successful only when the concentration of the platelets was high enough.
They inhibit blood clotting by blocking thromboxane formation in blood platelets.
The first few days ' blood tests showed high platelets, due to the many transfusions of platelets received during surgery.
Platelets are activated when an injury causes a blood vessel to break.
It is this aggregation of platelets which triggers the cascade of reactions leading to blood clot formation (thrombosis).
This recent microbiological research study gives new insight to the intracellular control mechanisms of platelets.
Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder caused by an abnormally low level of blood platelets, small disc-shaped cells essential to blood clotting (coagulation).
Coagulation, or clotting, is a complex process in which specific proteins found in blood plasma combine with other blood components, including platelets, to form clots and prevent blood loss.
Platelets are tiny colorless disc-shaped cells in the blood that collect (aggregate) in blood vessels to form a plug when a vessel is injured.
A deficiency in platelets or a disorder that affects platelet production can disrupt clotting and severely complicate blood loss from accidental injury, surgery, and specific diseases or conditions in which bleeding can occur.
In adults, ITP is considered an autoimmune disorder, which means that the body produces antibodies that damage some of its own products-in this case, blood platelets.
In addition to physically plugging breaks in blood vessel walls, platelets also release chemicals that promote clotting.
Thrombocytopenia-A persistent decrease in the number of blood platelets usually associated with hemorrhaging.
This may include transfusions of platelets, intravenous immunoglobulins, or prednisone.
Prednisone is a steroid medication that decreases the effects of antibodies on platelets and eventually lowers antibody production.
Bone marrow-The spongy tissue inside the large bones in the body that is responsible for making the red blood cells, most white blood cells, and platelets.
Blood is made up of red blood cells (RBCs), which carry oxygen and other materials to all tissues of the body; white blood cells (WBCs), which fight infection; and platelets, which play a part in the clotting of the blood.
These stem cells mature through stages into RBCs, WBCs, or platelets.
This uncontrolled proliferation of the immature cells in the bone marrow affects the production of the normal red blood cells and platelets as well.
Low level of platelets (tiny cellular elements in blood that are an important part of coagulation).
Plasma-A watery fluid containing proteins, salts, and other substances that carries red blood cells, white blood cells, and platelets throughout the body.
Whole blood-Blood which contains red blood cells, white blood cells, and platelets in plasma.
A platelet count is a diagnostic test that determines the number of platelets in the patient's blood.
Platelets, which are also called thrombocytes, are small disk-shaped blood cells produced in the bone marrow and involved in the process of blood clotting.
There are normally between 150,000-450,000 platelets in each micro-liter of blood.
Low platelet counts or abnormally shaped platelets are associated with bleeding disorders.
This increase is caused by a change in the shape of the platelets after removal from the body.
This period is the best time to count the sample when using electronic instruments, because the platelets will be within a standard size range.
Platelets can be observed in a direct blood smear for approximate quantity and shape.
Accurate assessment of the number of platelets requires other methods of counting.
For a proper count, the platelets should be evenly distributed in the hemacytometer.