noun
definition
The inactive precursor to plasmin; profibrinolysin
Examples of plasminogen in a Sentence
One such drug is called tissue plasminogen activator (alteplase) which is a clot-dissolving drug not yet in common use in the UK.
The majority of data are from trials using recombinant tissue plasminogen activator (rt-PA ), also known as alteplase.
Furthermore, we have identified uPA (urokinase-type plasminogen activator) as an anosmin-1 interactant.
These proteins convert plasminogen to plasmin, which in turn degrades fibrin, the main component of the clot.
The function of t-PA is to cleave a particular peptide bond in plasminogen, forming plasmin (which is itself a serine protease ).
The potential of uveal melanoma cell lines to convert plasminogen to angiostatin was tested in an in vitro assay.
Clot-busting medications, such as tissue plasminogen activator (t-PA, also called streptokinase enzymes or thrombolytic drugs), may be given to help dissolve the renal clot.