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A person who opens something.
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A device that opens something; specifically a tin-opener/can-opener, or a bottle opener.
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(in combination) An establishment that opens.
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(card games) The player who starts the betting.
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(card games, in the plural) Cards of sufficient value to enable a player to open the betting.
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(metalworking) A person employed to separate sheets of hot metal that become stuck together.
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(theater) The first act in a variety show or concert.
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(cricket) A batsman or bowler who normally plays in the first two positions of an innings.
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(colloquial) The first in a series of events, items etc.; the first remark or sentence of a conversation.
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(sports) The first game played in a competition.
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(sports) The first goal or point scored.
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(fishing) A period of time when it is legal to commercially fish.
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(baseball) A pitcher who specializes in getting the first outs of a game before being replaced, either by a long reliever or a pitcher who would normally start.