Word Finder - mutations

definition

Any alteration or change.

definition

Any heritable change of the base-pair sequence of genetic material.

definition

A mutant.

definition

An alteration a particular sound of a word, especially the initial consonant, which is triggered by the word's morphological or syntactic context and not by its phonological context.

definition

A group of thrushes.

The large fragment deletion mutations were located in a hot spot for deletion mutations were located in a hot spot for deletion that has been reported.

Alien genetic material invading genomes also give rise to gene mutations, some of which may result in cancer.

No specific measures can prevent the gene mutations that cause MPS.

As a consequence of co-evolution with their hosts, viruses have acquired host genes and genetic mutations that confer dominance over normal cell function.

The mechanism of other dominant mutations such as the one that causes myotonic dystrophy is not yet known.

Then twentieth-century biologists explained heredity and adaptation as a result of genes and mutations.

Members noted that mutations are found in all chemically induced cancers.

The results indicated a low frequency of microsatellite length mutations as the association was consistent across several breeds.

The attenuating mutation at residue 91 in VP3 is shown in cyan, and all suppressor mutations are shown in white.

Milder disease was observed in some cases carrying missense mutations as compared with those carrying truncating mutations.

These genes are often screened for somatic mutations only in the region most likely to contain mutations.

This project addresses how missense mutations are analyzed before an interpreted report is issued.

Missense mutation analysis This project is investigating the application of bioinformatic tools to determine the pathogenicity of unclassified missense mutations.

It was not able to induce point and frameshift mutations in haploid Saccharomyces cerevisiae cells.

However, the inserted transposon efficiently creates mutations in genes such as recessive oncogenes associated with cancer.

Single strand conformational polymorphism (SSCP) analysis and direct sequencing of TSG101 cDNAs also identified no mutations or deletions.

Mutations in DNA repair genes are strong candidates for at least a proportion of these unknown breast cancer predisposition alleles.

If the affected proband is homozygous or compound heterozygous suggest family screening (parents, siblings, children) for HFE mutations.

Underlying molecular defect CF is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein.

This data then allows us to design further mutations to achieve higher selectivity.

The organism can be cultured under defined conditions The organism is genetically tractable -- e.g., transformable, prone to introduction of designed mutations.

In mice, myosin V mutations lead to defects in synaptic transmission.

These changes and mutations only have an effect at the point where a new zygote is created.

Such mutations are not the product of the environment, but are an outcrop of the constitution of the germinal material of the varying organism, the result either of causes as yet undetected, or of the premutations and eliminations suggested by the work of Mendel (see Mendelism).

From this fundamental difference between the view held by history and that held by jurisprudence, it follows that jurisprudence can tell minutely how in its opinion power should be constituted and what power-- existing immutably outside time--is, but to history's questions about the meaning of the mutations of power in time it can answer nothing.

The team found the mystery protein through screening random mutations in mice.

One of the current challenges is the application of ribozyme therapy for dominant mutations coupled with wild-type gene augmentation to overcome haploinsufficiency.

Mutation analysis of 30 families that are affected by Lafora disease detected mutations in 10 families, which segregated with disease status.

These are both missense mutations, changing the valine residue at 287 to leucine 19 or to methionine 20.

In the most contaminated areas, aquatic animal and birds are directly affected, reducing their reproductive abilities, causing mutations, or killing them outright.

His mutations include an internal power generator and a cybernetic computer that regulates his abilities.

Cancer results from alterations (mutations) in genes that make up DNA, the master molecule of the cell.

Gene mutations can produce faulty proteins, which in turn produce abnormal cells that no longer divide and reproduce in an orderly manner.

Genetic testing uses molecular probes to identify gene mutations that have been linked to specific cancers.

Tumor-specific proteins that are part of unique genetic mutations in pediatric cancer, for example, are believed to be ideal targets for anti-tumor immune processes.

The mutations in this gene are point mutations because they involve a change (either deletion, substitution, or insertion) at one specific component of a gene.

However, the specific genes and the mutations have not yet been found as of 2004 for most types.

Because it has just been discovered, not much is known about how mutations in this gene cause CMT.

It is known as of 2004 that this is not a separate type of CMT; in fact, people who have onset in infancy or early childhood often have mutations in the PMP22 or MPZ genes.

More research is required to understand how mutations in these genes cause CMT.

As of early 2001, testing is available to detect mutations in PMP22, MPZ, Cx32 and EGR2.

Several gene mutations causing hereditary fructose intolerance have been identified.

Genetic testing with DNA analysis may be available to identify one of the common gene mutations that lead to this disorder.

Mutations in these genes can affect basic construction as well as the fine-tuned processing of the collagen.

Changes or mutations in genes can cause genetic diseases in several different ways, many of which are represented within the spectrum of EDS.

The rate of mutation of the fibrillin gene, however, appears to be related to the age of the child's father; older fathers are more likely to have new mutations appear in chromosome 15.

Between 15 and 25 percent of cases result from spontaneous mutations.

Mutations of the fibrillin gene (FBNI) are unique to each family affected by Marfan, which makes rapid genetic diagnosis impossible, given present technology.

Marfan syndrome that occurs because of spontaneous new mutations (15% to 25% of the cases) cannot be prevented.

Also, older fathers are more likely to have new mutations appear in chromosome 15.