noun
definition
The creation or formation of a genetic mutation.
Examples of mutagenesis in a Sentence
Another method of genetic modification, called mutagenesis, dates to the early part of the twentieth century.
Site directed mutagenesis has been used to generate such mutants.
We use site-directed mutagenesis to couple this information to structural features of the proteins.
Cloning, mutagenesis and expression The domains were amplified from cDNA using polymerase chain reaction (PCR ).
Our present study clearly demonstrates that anticancer chemotherapy can induce mutagenesis in vivo in various pediatric cancer patients.
We are using molecular genetic approaches, in particular random mutagenesis, to analyze fungal genes involved in the disease process.
For this we are using molecular modeling to investigate docking of the novel compounds, as well as conventional mutagenesis and expression techniques.
The mutants were generated by random transposon mutagenesis with the Tn pho A transposon.
The insertion mutagenesis strategy was co-ordinated with acquisition of the DNA sequence of the PAI.
Using this technique in combination with another mutagenesis method called saturation mutagenesis the ee value has been improved to more than 90 per cent.
One approach is to change the natural substrate specificity of an enzyme through mutagenesis.
The function of genes located by transposon mutagenesis and sequencing was tested after sub-cloning of open reading frames into broad host range shuttle vectors.