Word Finder - inhibitors

definition

One who or that which inhibits.

example

I found daily meditation to be a useful inhibitor of negative thoughts.

definition

Any substance capable of stopping or slowing a specific chemical reaction.

definition

Any substance capable of stopping or slowing a specific biological process

Apart from water pills, digoxin and warfarin, I have taken ACE inhibitors and now angiotensin II (candesartan ).

Treatment for kidney disease focuses on blood pressure control using ACE inhibitors.

Platelet transfusion through negatively charged filters can also activate the contact system and give rise to significant hypotension in patients receiving ACE inhibitors.

However, potatoes also contain a number of other inherent toxicants such as tropane alkaloids, terpenoids, saponins, protease inhibitors and lectins.

Many specialists already prescribe arbs to patients who cannot take ACE inhibitors.

Like ACE inhibitors, angiotensin II receptor blockers have also been shown to be beneficial in diabetic kidney disease.

By stopping this enzyme working, ACE inhibitors reduce the constriction of the blood vessels.

Care with ACE inhibitors is required in the presence of peripheral vascular disease or raised serum creatinine.

Drugs that induce cytochrome P450 activity may reduce the availability of some protease inhibitors by increasing first pass metabolism.

Stimulation of ACC oxidase activity " in vivo " by different effectors is differentially sensitive to inhibitors.

Both compounds are inhibitors of the HCV protease enzyme, which the virus uses to replicate itself.

The first medicines assessed for Alzheimer's treatment work in this way and are called acetylcholine esterase inhibitors.

The enzyme catalyzes the first step in carbon dioxide fixation in these plants and good inhibitors might be effective herbicides.

Future research is directed at evolution of the inhibitors of angiogenesis to combat neovascular glaucoma.

This will be achieved by implanting beads containing the relevant growth factors or pharmacological inhibitors of signaling pathways.

The anhydrides 1b - 1d are much more efficient inhibitors of GGPTase-I than are the corresponding succinic acids (obtained by hydrolysis ).

Other inhibitors that have been identified include a number of inhibitors of apoptosis or " IAPs " .

Several trials have shown that ace inhibitors improve survival in patients with all grades of heart failure.

The two drugs covered by last year's trials were COX-2 inhibitors.

Sumatriptan must not be used within two weeks of discontinuation of therapy with monoamine oxidase inhibitors.

More recently a number of non-nucleoside reverse transcriptase inhibitors (NNRTIs) have been introduced.

The buzz, of course, was all about protease inhibitors.

Prescribing patterns of selective serotonin reuptake inhibitors in primary care in the United Kingdom.

In the 1990s research for new antidepressant medications focussed on serotonin uptake inhibitors to rival Prozac's phenomenal success.

A variety of changes were identified that are common to HMG-CoA reductase inhibitors, viz.

Hence, strong inhibitors of this enzyme may inhibit the metabolism of clarithromycin, resulting in increased plasma concentrations of clarithromycin.

It should also not be used in patients receiving monoamine oxidase (MAO) inhibitors or patients on certain antidepressants.

The delivery of dual inhibitors linked by the galactose oxidase linker showed a clear additive effect over either inhibitor delivered singly.

Links to Ensembl The Summaries for human and mouse peptidases and inhibitors now contain links to gene reports in the Ensembl database.

Investigate the nature of the inhibition using the enzyme phosphatase and the inhibitors phosphate and iodine.

Chiroscience has made a series of medicines called purine nucleoside phosphorylase (PNP) inhibitors which have shown promise in animal models of arthritis.

Because of their effect on renal prostaglandins, cyclo-oxygenase inhibitors such as naproxen can increase the nephrotoxicity of cyclosporin.

The Federal Drug Agency approved the first of a potent new family of anti-HIV drugs called protease inhibitors.

Four posters reported findings from studies evaluating PK parameters of two commonly used protease inhibitors and the nucleotide analog tenofovir in pregnancy.

As well as phytoestrogens, soya contains protease inhibitors which have been shown to block cancer-causing protease enzymes.

Hyperglycaemia New onset diabetes mellitus, hyperglycaemia, and exacerbation of existing diabetes mellitus have been reported in patients receiving protease inhibitors.

It's thought these complications are caused by protease inhibitors blocking the elimination of corticosteroids leading to higher concentrations in the blood.

This will also be true for other protease inhibitors.

The new drug will be indicated for highly pre-treated adults with virus resistant to multiple protease inhibitors.

We have characterized a number of cDNAs which encode proteinases to underpin optimization of proteinase inhibitors either alone or in combination.

We have used the paradigm of rational design from structural information to engineer more potent cysteine proteinase inhibitors offer.

We are studying the structural biology of members of the serpin family of serine proteinase inhibitors using X-ray crystallography.

Pre-existing proteinuria may deteriorate (tho ACE inhibitors usually reduce proteinuria ), or there may be an increase in urinary output.

These are all drugs known as nucleoside analogs, nucleoside reverse transcriptase inhibitors (NRTIs ).

The second group, the 5-alpha reductase inhibitors carry out their work by blocking the production of the main hormone responsible for prostate enlargement.

Reverse transcriptase inhibitors have been available for many years now, but protease inhibitors are new.

These are all drugs known as nucleoside analogs, nucleoside reverse transcriptase inhibitors (NRTIs).

A study has been made of squalene synthase inhibitors by an EPSRC funded PhD student and support from Pfizer, Kent.

The enzyme is found in most types of tumor cells but not in healthy cells, indicating the potential of telomerase inhibitors in chemotherapy.

An example of the use of simple molecules for directed screening for thrombin inhibitors will be presented.