definition
(dog-breeding) A female dog or other canine, particularly a recent mother.
example
My bitch just had puppies; they're so cute!
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A promiscuous woman, slut, whore.
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A despicable or disagreeable, aggressive person, usually a woman.
example
Ann gossiped about me and mocked my work; sometimes she can be a real bitch!
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A woman.
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A man considered weak, effeminate, timid or pathetic in some way
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A submissive person who does what others want; a man forced or coerced into a homoerotic relationship.
example
Dude, don't be such a bitch. Assert yourself.
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(of a man) A playful variation on dog (sense "man").
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(used with a possessive pronoun) Friend.
example
How my bitches been doin'?
definition
A complaint, especially when the complaint is unjustified.
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(usually only used in the singular) A difficult or confounding problem.
example
Level 5 was a real bitch, don’t you think?
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A queen (playing card), particularly the queen of spades in the card game of hearts.
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Something unforgiving and unpleasant.
example
Karma's a bitch.
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Place; situation