Word Finder - genes

definition

A theoretical unit of heredity of living organisms; a gene may take several values and in principle predetermines a precise trait of an organism's form (phenotype), such as hair color.

definition

A segment of DNA or RNA from a cell's or an organism's genome, that may take several forms and thus parameterizes a phenomenon, in general the structure of a protein; locus.

example

A change in a gene is reflected in the protein or RNA molecule that it codes for.

With more than thirty thousand genes in your body, you can't expect them all to have cool names.

This gives considerable impetus to the search for genes involved.

Genes are a chemical alphabet held in every cell of the body.

For genes and genomes to maintain dynamic constancy, there must be a balanced ecology.

In reality, androgenetic alopecia might depend on more or fewer than four genes, each of which might contribute variably to predisposition.

In the germline DNA, the V genes encoding the antigen combining sites need to combine with the C genes.

The transposon used contains splice acceptors in both orientations to disrupt the expression of genes in which it lands.

They thus provide a useful adjunct to cDNA libraries in giving access to a large number of genes independent of developmental stage.

The pattern of familial aggregation suggests that in individual families, a small number of genes act together to cause the phenotype.

For example, genes from the bacterium bacillus thuringiensis produce a toxin that kills certain insects.

All of our horses are selected from proven genes using only the very best bloodlines.

We have already isolated many genes that are expressed more in PD brains than in controls.

We're too brainy for our genes to maintain control, except by fluke.

In the case of the color genes of interest to budgerigar breeders, the effects of most single color influencing genes is dramatic.

Our early work established mutations in genes encoding members of the visual transduction cascade as important in these diseases.

We are now using expression profiling in wildtype and Gli3 mutant mice to identify novel Wnt target genes in the developing cerebral cortex.

Apparently genes do not stand at the undisputed head of a causal chain.

Each operon has some genes which encode cytoplasmic rather than membrane spanning chemoreceptors.

Insulators are DNA elements that defend genes from surrounding chromatin by setting the boundaries of independent chromatin domains.

Fruit flies also have large polytene chromosomes, whose barcode patterns of light and dark bands allow genes to be mapped accurately.

Genes isolated from the area using cDNA clones might be incomplete.

The spread of genes linked to this promoter by ordinary cross-pollination or by horizontal gene transfer will have enormous impacts on health and biodiversity.

The genome sequence is available for this bacterial strain, revealing genes that encode 39 c -type cytochromes.

To provide for efficient delivery of the cytokine, adenovirus vectors have been proposed to deliver the cytokine genes to the chicken.

In thalassaemia there is an inherited defect in one of these genes.

Nitrogen fixation genes can also be added, thus reducing need for artificial fertilizers.

Each child of such parents has a 25 percent chance of inheriting both genes and showing signs of the disease, and a 50 percent chance of inheriting one defective gene from only one parent.

Although genes may be a factor in a child's social competence and level of peer acceptance, environmental factors are also extremely important.

As genes are identified that result in the disorders, genetic testing is being developed to identify carriers, who then can manage their reproduction to avoid the possibility of children being born with these deficiencies.

Autosomal recessive mutation-A pattern of genetic inheritance where two abnormal genes are needed to display the trait or disease.

Some candidate genes for TS have also been tested and excluded.

Genes such as tumor suppressor genes tightly regulate this growth cycle.

If both RB1 genes in a retinal cell become non-functional, then a retinal cell can become cancerous and retinoblastoma can result.

In other cases, one parent has two normal RB1 genes in every somatic cell, but some egg or sperm cells contain a changed or missing RB1 gene.

Retinoblastoma can also result when both RB1 genes become spontaneously changed or deleted in a retinal cell but the RB1 genes are normal in all the other cells of the body.

This testing can usually identify the gene changes/deletions in the RB1 genes that caused the tumor to develop.

If the changes in both RB1 genes are detected in the tumor cell, then these same changes can be looked for in the blood cells.

A child may inherit thalassemia trait when only one parent has the genes responsible for it.

Thalassemia major (homozygous thalassemia or Cooley's anemia) occurs in children in whom both parents pass on the genes responsible.

Hemoglobin H disease is another form of thalassemia in which three of the four beta-globin genes are missing.

These findings suggest the potential role of one or more genes being responsible for clubfoot.

Alkylating drugs-kill cancer cells by directly attacking DNA, the genetic material of the genes.

Two spots (called loci) on these genes control alpha globin production.

Alpha thalassemias result from changes (mutations) in these genes.

Individuals with alpha thalassemia major have inherited two completely defective genes, one from each parent.

Individuals of Greek, Middle Eastern, and North African descent also carry genes for the disease more frequently than individuals of Northern European descent.

Since there are four genes (instead of the usual two) to consider when looking at alpha globin gene inheritance, there are several alpha globin types that are possible.

Alpha thalassemia trait occurs when two alpha globin genes are missing or not functioning.

This syndrome can be caused by a deletion of a significant amount of chromosome 16, affecting the alpha globin genes.

Alpha thalassemia major results from the deletion of all four alpha globin genes, such that there are no functioning alpha globin genes.