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An opening in anything made by breaking or parting.
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An opening allowing passage or entrance.
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An opening that implies a breach or defect.
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A vacant space or time.
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A hiatus, a pause in something which is otherwise continuous.
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A vacancy, deficit, absence, or lack.
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A mountain or hill pass.
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(Sussex) A sheltered area of coast between two cliffs (mostly restricted to place names).
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(baseball) The regions between the outfielders.
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(Australia, for a medical or pharmacy item) The shortfall between the amount the medical insurer will pay to the service provider and the scheduled fee for the item.
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(Australia, usually written as "the gap") The disparity between the indigenous and non-indigenous communities with regard to life expectancy, education, health, etc.
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(genetics) An unsequenced region in a sequence alignment.
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(slang, euphemistic) The vagina.