noun

definition

A white, albuminous, fibrous substance, formed in the coagulation of the blood.

definition

An elastic, insoluble, whitish protein produced by the action of thrombin on fibrinogen and forming an interlacing fibrous network in the coagulation of blood.

definition

An albuminous body, resembling animal fibrin in composition, found in cereal grains and similar seeds; vegetable fibrin.

verb

definition

To apply fibrin sealant to a surgical site to either stop bleeding or for surgical flap closure.

Examples of fibrin in a Sentence

Fibrinogen occurs in the blood plasma, and is changed by a ferment into fibrin, to which the clotting of blood is due.

Lying between the fibrin mass and the healthy tissues is a zone of injured and degenerated tissue elements, the result of the trauma.

Next, blood coagulation rapidly replaces this unstable platelet plug with a stable fibrin clot.

Haemostatic mechanisms control blood flow by regulating platelet adherence and fibrin deposition and various haemostatic proteins have been shown to regulate angiogenesis.

Blood clots (thrombi) are clumps of a naturally-occurring protein called fibrin which can accumulate in a blood vessel.

These proteins convert plasminogen to plasmin, which in turn degrades fibrin, the main component of the clot.

Previous research has shown that fibrin accumulates in the damaged nerves of MS patients.

Explain how blood clots by platelets producing thrombin, which converts soluble fibrinogen into insoluble fibrin.

Fatal anaphylaxis followed aprotinin exposure in a local application of fibrin glue [22] .

The vegetation that characterizes IE is composed of a mixture of fibrin and platelets, containing a large inoculum of bacteria.

Venous thrombi are formed by stasis and are mainly composed of red blood cells intertwined with fibrin.

The natural agent in vampire bat saliva becomes 13,000 times more active when exposed to fibrin.

The factors include prothrombin, thrombin, and fibrin.

Prothrombin, under the right conditions, is converted to thrombin, which activates fibrin and begins the process of coagulation.

The final plug or clot involves tightly woven fibers of a material called fibrin.

Various diagnostic tests are available to measure, under carefully controlled conditions, the length of time it takes to produce certain components of the final fibrin clot.

Fibrin forms strands that add bulk to a forming blood clot to hold it in place and help "plug" an injured blood vessel wall.

Fibrin, produced from fibrinogen by a ferment, is a jelly-like substance, coagulable by heat, alcohol, &c. The muscle-albumins include " myosin " or paramyosinogen, a globulin, which by coagulation induces rigor mortis, and the closely related " myosinogen " or myogen; myoglobulin and myoalbumin are also found in muscles.

As the edges of the wound are brought into accurate apposition there is little or no blood lodged between them, so that an extremely narrow strip of fibrin glues the cut edges together.

It is believed also that they secrete bactericidal substances and ferments which bring about the liquefaction of the fibrin and the damaged tissues - histolysis - and thus assist the process of absorption.

Numerous fibroblasts, together with polyblasts, are visible in the fibrin mass, and the vessels at the periphery of the damaged zone are now seen to be sending out offshoots which assist in the process of absorption.

The primary PA involved in intravascular fibrin degradation is tPA.

Fibrin creates a number of threads that make the plasma sticky, enabling a clot to form.

A natural process in which blood cells and fibrin strands clump together to stop bleeding after a blood vessel has been injured.

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