noun
definition
A sedative drug used to treat schizophrenia.
Examples of clozapine in a Sentence
Clozapine, an atypical neuroleptic agent with D 4 receptor antagonist activity, does not cause tardive dyskinesia but may cause agranulocytosis.
This is of potential clinical importance for products with a narrow therapeutic window, e.g. theophylline, clozapine and ropinirole.
A major breakthrough in the treatment of schizophrenia occurred in 1990 with the introduction of the drug clozapine to the U.S. market.
However, even clozapine does not work for all patients.
In addition, about 1 percent of those who take it develop agranulocytosis, a potentially fatal blood disease, within the first year of use, and all patients on clozapine must be monitored regularly for this side effect.
Risperidone, a subsequent and safer medication that offers benefits similar to those of clozapine, was introduced in 1994 and is as of the early 2000s the most frequently prescribed antipsychotic medication in the United States.
Adolescents diagnosed with IED have been reported to respond well to clozapine (Clozaril), a drug normally used to treat schizophrenia and other psychotic disorders.
Clozapine (Clozaril) is an atypical antipsychotic medication used to control manic episodes in adult patients who have not responded to typical mood stabilizing agents.
Common side effects of clozapine include tachycardia (rapid heart rate), hypotension, constipation, and weight gain.
Agranulocytosis, a potentially serious but reversible condition in which the white blood cells that typically fight infection in the body are destroyed, is a possible side effect of clozapine.