noun
definition
A linear arrangement of condensed DNA and associated proteins (such as chaperone proteins) which contains the genetic material (genome) of an organism.
example
Chromosomes store genetic information.
Examples of chromosome in a Sentence
As they pass into this position they undergo a longitudinal splitting by which the chromatin in each chromosome becomes divided into equal halves.
I also have a report by Dr. Tartaglia on girls with a chromosome anomaly.
The sperm carries either another X or a Y chromosome.
A typical breast cancer, for example, will have 10 to 20 chromosome aberrations.
By studying the reading and writing abilities of close to 80 family members across four generations, the researchers reported, for the first time, that chromosome 2 can be involved in the inheritability of dyslexia.
There is also a type of ocular albinism that is carried on the X chromosome and occurs almost exclusively in males because they have only one X chromosome and, therefore, no other gene for the trait to override the defective one.
Partial trisomy of the proximal segment of chromosome 13 is much less likely to be fatal and has been associated with a variety of facial features including a large nose, a short upper lip, and a receding jaw.
Female children, on the other hand, have two copies of the X chromosome, which often leaves them one normal X chromosome to fall back on to produce that essential protein, allowing proper development to occur.
Each chromosome is really a very long DNA molecule.
However, it is estimated that 3 to 8 percent of girls with a single X chromosome and 12 to 21 percent of females with sex chromosome mosaicism may have normal pubertal development and spontaneous menstrual periods.
If there is a green allele on chromosome 19 and the rest of the allele on chromosome 19 and the rest of the alleles are blue, eye color will be green.
Three major histocompatibility antigens are encoded on each copy of chromosome 6, but they are inherited as a group.
Press Release | Sequence Data | Nature Article | Author List About Chromosome 22 Chromosome 22 is the second smallest of the human autosomes.
They each consist of two threads called chromatids, each an exact copy of the parent chromosome.
Each chromosome has divided to produce 2 identical chromatids, joined at a structure called the centromere.
Each chromosome is really a very long molecule of DNA wound up and coiled around special proteins to form chromatin.
The whole region has been physically mapped to porcine chromosome 6 using in situ hybridisation.
The Plasmodium falciparum chromosome 2 project was funded by the National Institute of Allergy and Infectious Diseases (NIAID ).
With this strategy variations between metaphases due to different chromosome condensation can be minimized.
We attempted to characterize these chromosome 13q deletions at the molecular cytogenetic level.
The allelic deletions on chromosome arms 15q and 16q have not been defined previously for SCLC and are candidate regions to harbor novel TSGs.
This approach permitted the simultaneous evaluation of ploidy changes and chromosome arm deletions.
A mutation in a receptor for the neurotransmitter dopamine has been found on chromosome 11 or 18.
The genes coding for the alpha globins are on chromosome 11; those coding for the beta globins are on chromosome 16.
Blood Chromosome Analysis This is performed on a 5-10ml fresh, sterile sample of venous blood in a lithium heparin container.
This allows the simultaneous analysis of every chromosome for submicroscopic chromosome imbalances using only a single slide per patient.
Human Genome Project; Human chromosome launchpad The Human Chromosome Launchpad provides links to research resources for each human chromosome.
Josh Eaton's Home Page A 7 year old who has had a bone marrow transplant for Philadelphia chromosome positive acute lymphoblastic leukemia.
The MBL2 gene on chromosome 10 is the blueprint for a protein called mannose binding protein that is similar in shape to C1q.
Therefore mutation provides a mechanism for adding random genetic material into the chromosome by changing one or more of the gene values at random.
To study meiosis, it is necessary to investigate the consequences to chromosome segregation of altering particular proteins.
Our studies also suggest the existence of another processed pseudogene on chromosome 11.
David Perkins gave an overview of the study of fungal chromosome rearrangements.
They also provide a binding point outside of the main chromosome where replication of the chromosome ends can occur from.
The production of gametes, be they sperm in males or eggs in females, requires major changes in the mechanism of chromosome segregation.
Analysis of the " X " chromosome - the female sex chromosome - has revealed that women are genetically more complicated than men.
Almost a third of adult patients have a specific chromosome translocation; " Philadelphia Positive " ALL.
Parental chromosome analysis should be offered where trisomy 13 is due to an unbalanced translocation.
The bollworm was modified using the piggyBac transposon that inserts at the sequence, TTAA in the chromosome (see above ).
Vega database for dog contains 700 kbp of the MHC region on chromosome 12 comprising fully annotated clones only.
Visible differences in the chromosomes have even been observed, especially in insects, which are due apparently to an unequal division by which an additional or accessory chromosome is produced, or in some cases one or two extra chromosomes which differ in size from the others.
From numerous investigations which have been made to trace the chromosomes through the various stages of the nuclear ontogeny of plant cells, it appears that the individuality and continuity of the chromosomes can only be conceived as possible if we assume the existence of something like chromosome centres in the resting nucleus around which the chromosomes become organized fon purposes of division.
The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.
The DNA sequence of the human Y chromosome - the ' maleness ' chromosome - has been published.
Parents were almost always not prepared for the possibility of a sex chromosome anomaly and reacted with confusion.
Future directions Several challenges now face those researching spermatogenesis genes on the Y chromosome.
A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10.
The bollworm was modified using the piggyBac transposon that inserts at the sequence, TTAA in the chromosome (see above).
The other fuses with genetic material in the ovule to produce a triploid tissue (has three copies of each chromosome).
Dog The vega database for dog contains 700 kbp of the MHC region on chromosome 12 comprising fully annotated clones only.