noun
definition
A reversion of differentiation in cells that is characteristic of malignancy in tumours.
Examples of anaplasia in a Sentence
Patients with the favorable type of cell have a long-term survival rate of 93 percent, whereas those with anaplasia have a long-term survival rate of 43 percent and those with the sarcoma form have a survival rate of 36 percent.
Hansemann's "anaplasia " hypothesis seeks to find an explanation of the formation of new growths in the absence of the histological differentiation of the cell associated with a corresponding increase in its proliferative power and a suspension, or loss, of its functional activity.
The greater the degree of anaplasia the more the tumour cells conform in character and appearance to the embryonic type of cell and the more malignant is the new growth.